Why Save Cord Blood - Cordlife Singapore
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Benefits of Saving Cord Blood

There are many reasons why you should store your baby's cord blood stem cells. They include:

A guaranteed match for autologous transplants (where the donor and recipient are the same individual).

Autologous stem cell transplants refer to transplants where the donor and recipient of the stem cells are the same individual. The cord blood that you are storing for your baby today is a potential medical resource for the future, and does not require stringent matching as opposed to conventional bone marrow stem cell transplants.

In Singapore, 40% – 60% of patients1 who require a stem cell transplant are unable to find a suitable match from bone marrow donors or the public cord blood bank each year. The odds of finding a match within the same racial group is only 1 in 20,0002.

A Readily Available Supply of Stored Haematopoietic Stem Cells.

In the event of an already time-critical situation where stem cells are required for a transplant, having your child’s cord blood stored compares well to having to do a national or international search which is both costly and time-consuming. The cost of procuring a cord blood sample in Singapore can cost up to $75,0003, and that is, if a match is found.

Lower risk of Graft vs. Host Disease (GvHD) for autologous transplants.

Using stem cells from cord blood also minimises the risk of Graft vs Host Disease (GvHD) for autologous transplants (where the donor and recipient are the same individual) as compared to unrelated donor transplants.

GvHD is a condition where the transplanted tissue cells (the graft) sees the patient’s own tissue (the host) as foreign and attacks them.

Up to 75% Chance of Genetic Match For Siblings4

The umbilical cord blood from a sibling offers a lifetime of protection for the family as the stored cord blood offers a higher potential for genetic matches. Many families have benefited from using sibling stem cells for treatment.

Umbilical cord blood stem cells are younger and more primitive.

In comparison to other types of stem cells obtained from other sources, e.g. bone marrow and peripheral blood, umbilical cord stem cells are able to grow healthy blood stem cells at a faster rate5,6 and are also more tolerant to HLA* mismatches7.
*Human leukocyte antigens (HLAs) are proteins that help the body's immune system tell the difference between its own cells and foreign, harmful substances.
Source: https://medlineplus.gov/ency/article/003551.htm

Ease of collection, which is pain-free and risk-free to both mother and child.

Cord blood collection is a relatively easy task, which is handled by your own delivering doctor (OBGYN). This process does not affect the birthing process in any way and can be done on both natural and c-section births.

References:

1 Treatment with cord blood page. Singapore Cord Blood Bank website. https://www.scbb.com.sg/cordblood/pages/treatment-with-cord-blood.aspx. Accessed July 23, 2021.
2 Yuen S. Wanted: More bone marrow donors from minority races. The Straits Times. September 18, 2016:13.
3 Criterion for new stem-cell transplant 50 per cent match. AsiaOne website. https://www.asiaone.com/health/criterion-new-stemcell-transplant-50-cent-match. Accessed July 23, 2021.
4 Jawdat D, Saleh S, Sutton P, Anazi H, Shubaili A, Tamim H, et al. Chances of Finding an HLA-Matched Sibling: The Saudi Experience. ScienceDirect. 2009;15(10): 1342-1334.
5 Bordeaux-Rego P, Luzo A, Costa FF, et al. Both interleukin-3 and interleukin-6 are necessary for better ex vivo expansion of CD133+ cells from umbilical cord blood. Stem Cells Dev. 2010;19(3):413–422.
6 Kadereit S, Deeds LS, Haynesworth SE, et al. Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34+/CD38− early progenitors cultured over human MSCs as a feeder layer. Stem Cells. 2002;20(6):573–582.
7 Beksac M (2016) Is There Any Reason to Prefer Cord Blood Instead of Adult Donors for Hematopoietic Stem Cell Transplants? Front. Med. 2:95. doi: 10.3389/fmed.2015.00095 .

DCR No. 4380, August 2021

Cordlife’s consultation booths located at Mount Elizabeth Novena Hospital, Parkway East Hospital and Thomson Diagnostic Ultrasound Centre have reopened with a change in opening hours and Safe Management Measures in place. To find out more, please click here. Our friendly sales consultants are available through web consultations should you have any questions about our services and/or are interested to store your baby’s umbilical cord stem cells with us.

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