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Over 80 diseases1 potentially treatable
with cord blood stem cells

Stem cells are now at the forefront of one of the most fascinating and revolutionary fields in medicine. Blood-forming stem cells, also called Haematopoietic Stem Cells (HSCs), can be found in your baby's cord blood. These cells have the potential to treat more than 80 diseases1, including some types of cancer like leukaemia, neuroblastoma, and lymphoma.

During a stem cell transplant, stem cells are infused into the patient’s bloodstream, where they start to heal damaged cells and tissues. The patient’s blood and immune system are regenerated after the stem cells successfully engraft.


Haematopoietic Stem Cells (HSCs) can potentially be used to treat over 80 diseases1

List of diseases potentially treatable with cord blood stem cells

The following diseases can potentially be treated with cord blood stem cell transplants. These cells can be derived from cord blood, bone marrow, or peripheral blood.

Blood Cancers
Blood Cancers
STANDARD THERAPIESAllogeneicAutologous
Acute Biphenotypic LeukaemiaX
B-cell Acute Lymphoblastic Leukaemia 2X
T-cell Acute Lymphoblastic Leukaemia 2X
Acute Myelogenous LeukaemiaX
Acute Undifferentiated LeukaemiaX
Chronic Myelogenous LeukaemiaX
Chronic Lymphocytic LeukaemiaX
Juvenile Myelomonocytic LeukaemiaX
Juvenile Chronic Myelogenous LeukaemiaX

Myeloproliferative Neoplasms
STANDARD THERAPIESAllogeneicAutologous
Acute MyelofibrosisX
Agnogenic Myeloid Metaplasia (Myelofibrosis)X
Essential ThrombocythemiaX
Polycythemia VeraX
Myelodysplastic Syndromes
STANDARD THERAPIESAllogeneicAutologous
Refractory AnaemiaX
Refractory Anaemia with Excess BlastsX
Refractory Anaemia with Excess Blasts in TransformationX
Refractory Anaemia with Ringed Sideroblasts (Sideroblastic Anaemia)X
Chronic Myelomonocytic LeukaemiaX
Bone Marrow Cancers
STANDARD THERAPIESAllogeneicAutologous
Multiple MyelomaXX
Plasma Cell LeukaemiaXX
Waldenstrom’s MacroglobulinemiaXX
Non Malignant Blood Disorders
Non Malignant Blood Disorders
Anaemias (Deficiencies or Malformations of Red Cells)
STANDARD THERAPIESAllogeneicAutologous
Aplastic AnaemiaX
Congenital Dyserythropoietic AnaemiaX
Fanconi Anaemia3X
Paroxysmal Nocturnal HemoglobinuriaX
Inherited Red Cell Abnormalities
STANDARD THERAPIESAllogeneicAutologous
Pure Red Cell AplasiaX
Sickle Cell AnaemiaX
Beta Thalassemia Major / Cooley’s AnaemiaX
Diamond Blackfan AnaemiaX
Inherited Platelet Abnormalities
STANDARD THERAPIESAllogeneicAutologous
Amegakaryocytosis / Congenital ThrombocytopeniaX
Glanzmann’s ThrombastheniaX
Immune Disorders
Immune Disorders
Severe Combined Immune Deficiencies (SCID)
STANDARD THERAPIESAllogeneicAutologous
Omenn SyndromeX
SCID with Adenosine Deaminase Deficiency (ADA SCID)X
SCID which is X linkedX
SCID with absence of T & B CellsX
SCID with absence of T Cells, Normal B CellsX
Inherited Disorders of the Immune System & Other Organs
STANDARD THERAPIESAllogeneicAutologous
Cartilage Hair HypoplasiaX
Erythropoietic PorphyriaX
Hermansky Pudlak SyndromeX
Pearson’s SyndromeX
Shwachman Diamond SyndromeX
Systemic MastocytosisX
Phagocyte Disorders
STANDARD THERAPIESAllogeneicAutologous
Chediak Higashi SyndromeX
Chronic Granulomatous DiseaseX
Neutrophil Actin DeficiencyX
Reticular DysgenesisX
STANDARD THERAPIESAllogeneicAutologous
Kostmann Syndrome (Infantile Genetic Agranulocytosis)X
Other Inherited Immune System Disorders
STANDARD THERAPIESAllogeneicAutologous
Bare Lymphocyte SyndromeX
Common Variable ImmunodeficiencyX
DiGeorge SyndromeX
Hemophagocytic LymphohistiocytosisX
IKK Gamma Deficiency4,5 (NEMO Dificiency)X
IPEX Syndrome6,7X
Leukocyte Adhesion DeficiencyX
Wiskott Aldrich SyndromeX
Lymphoproliferative DisordersX
X linked Lymphoproliferative Disease (Duncan’s Syndrome)X
Metabolic Disorders
Metabolic Disorders
Leukodystrophy Disorders
STANDARD THERAPIESAllogeneicAutologous
Adrenoleukodystrophy (ALD)X
Krabbe Disease (Globoid Cell Leukodystrophy)X
Metachromatic LeukodystrophyX
Pelizaeus-Merzbacher DiseaseX
Lysosomal Storage Diseases
STANDARD THERAPIESAllogeneicAutologous
Niemann Pick DiseaseX
Sandhoff DiseaseX
Wolman DiseaseX
Mucopolysaccharidosis (MPS) Storage Diseases
STANDARD THERAPIESAllogeneicAutologous
Hunter SyndromeX
Hurler SyndromeX
Maroteaux Lamy SyndromeX
Mucolipidosis II (I-cell Disease)X
Morquio SyndromeX
Sanfilippo SyndromeX
Scheie SyndromeX
Sly Syndrome (beta-glucuronidase deficiency)X
Other Metabolic Disorders
STANDARD THERAPIESAllogeneicAutologous
Lesch–Nyhan SyndromeX
Solid Tumors
Solid Tumors
STANDARD THERAPIESAllogeneicAutologous
Hodgkin's LymphomaXX
Non Hodgkin's Lymphoma (Burkitt’s Lymphoma)X

Storing cord blood does not guarantee that the cells will provide a cure or be useful in all situations. The treating physician will ultimately decide if cord blood can be used.


1 Diseases treated page. Parent’s Guide to Cord Blood Foundation website. Accessed December 5, 2022.
2 B-cell and T-cell acute lymphoblastic leukemia page. Mayo Clinic Laboratories website.,2%E2%80%935%20years%20of%20age. Accessed June 28, 2023.
3 Bizzetto R, Bonfim C, Rocha V, et al. Outcomes after related and unrelated umbilical cord blood transplantation for hereditary bone marrow failure syndromes other than Fanconi anemia. Haematologica. 2011; 96(1):134-141.
Picard C, J-L Casanova, Puel A, Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα Deficiency. Clin. Microbiol. Rev. 2011; 24(3):490-497.
5 Tono C, Takahashi Y, Terui K, et al. Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen. Bone Marrow Transplant. 2007;39(12):801-804.
6 Immunodysregulation polyendocrinopathy enteropathy X-linked (IPEX) Syndrome page. Stanford Children’s Health website. Accessed December 5, 2022.
7 Rao A, Kamani N, Filipovich A, et al. Successful bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning. Blood. 2007; 109(1):383-385.

Clinical trials

Below are some of the diseases1 that are currently undergoing clinical trials using blood-forming cells or cord blood. As researchers continue to push the boundaries of stem cells for some of the most common life-threatening diseases, saving your baby's cord blood now will give your child access to her own stem cells once these therapies are available. For the complete and most updated list, please visit

Auto Immune Disorders
Auto-Immune Disorders
STANDARD THERAPIESAllogeneicAutologous
Alopecia AreataX
Amyotrophic Lateral Sclerosis (ALS)X
Crohn’s DiseaseX
Eczema (Atopic Dermatitis)X
Graft-versus-Host Disease (GvHD)X
Multiple SclerosisX
Rheumatoid ArthritisX
Systemic SclerosisX
Ulcerative ColitisX
Genetic or Metabolic Disorder
Genetic and/or Metabolic Disorder
STANDARD THERAPIESAllogeneicAutologous
Aging FrailtyX
Duchenne Muscular DystrophyX
Epidermolysis BullosaX
Gaucher’s Disease4X
Hereditary AtaxiaX
Lysosomal Storage DiseasesX
Metabolic SyndromeX
Severe Combined ImmunodeficiencyX
Spinal muscular atrophyX
Tay-Sachs DiseaseX
STANDARD THERAPIESAllogeneicAutologous
Acute Myocardial Infarction (Heart Attack)X
Critical Limb Ischemia (CLI)X
Heart FailureX
Hypoplastic Left Heart Syndrome2X
Ischemic Heart Disease3X
Peripheral Arterial Disease (PAD)X
Surgery for Congenital Heart DefectsX
STANDARD THERAPIESAllogeneicAutologous
Ankylosing SpondylitisX
Cartilage InjuryX
Cleft Palate RepairX
Non-Union FracturesX
Osteochondral LesionX
Spinal Fusion SurgeryX
STANDARD THERAPIESAllogeneicAutologous
Diabetes, Type 1 (Auto-Immune)XX
Diabetes, Type 2XX
Diabetic Foot UlcerX
Diabetic Peripheral NeuropathyX
Neurologic Disorder
Neurologic Disorder
STANDARD THERAPIESAllogeneicAutologous
Alzheimer’s DiseaseX
Cerebral PalsyXX
Global Developmental DelayXX
Hearing Loss (acquired sensorineural)X
Intraventricular HemorrhageXX
Parkinson’s DiseaseX
Spinal Cord InjuryX
Traumatic Brain InjuryXX
STANDARD THERAPIESAllogeneicAutologous
Acute Respiratory Distress Syndrome (ARDS)X
Bronchopulmonary Dysplasia (BPD) (lung disorder due to premature birth)X
Erectile DysfunctionX
Eye DiseasesX
Kidney FailureX
Liver CirrhosisX
Liver FailureX
Ovarian Cancer6X
Peyronie’s DiseaseX
Premature Ovarian FailureX
Testicular Tumour7X
Uterine ScarsX

*The clinical trials listed above may use cell lines other than Haematopoietic Stem Cells, such as Mesenchymal Stem Cells.

A majority of autologous infusions/regenerative applications listed above were performed under clinical trial.


1 Therapies in clinical trials page. Parent’s Guide to Cord Blood Foundation website. Accessed December 5, 2022.

2 registry… NCT01883076, NCT03431480, NCT03779711. Last accessed December 5, 2022.

3 Umbilical cord derived mesenchymal stem cell therapy in ischemic cardiomyopathy page. website. Accessed December 5, 2022.

4 registry… NCT00176904, NCT04528355. Last accessed December 5, 2022.

5 Mesenchymal stem cells and COVID-19: Cure, prevention, and vaccination page. website. Accessed December 5, 2022.

6 Cady C., McAsey M., Li J. Progress towards a stem cell based therapy for ovarian cancer – Proceeding of the STEMSO Conference. Accessed December 5, 2022.

7 High-dose chemo & stem cell transplant for testicular cancer page. American Cancer Society website. Published May 17, 2018. Accessed December 5, 2022.

.DCR No. 4990, Version K, September 2023 (reference from QR 8.1-8-5-J)